Cardiac conduction system: the graph theoretic approach

Nzerem Francis Egenti, Ugorji Hycinth Chimezie

Abstract


Cardiac conduction system (CCS) describes the mode of transmission of ionic current through the cardiac myocytes. An unperturbed conduction system is required for the integrity of blood flow and for the prevention of cardiac events. In keeping with the CCS as an electrical system, this paper treated the ionic current as an electrical circuit flow with nodal and conducting structures. This is not novel. What may be unique and appealing is the graph theoretic method by which the work is couched. As electric current is a directed flow, directed graph (digraph) theory was used in the conduction system schematics, which in turn aided the resulting matrix analysis. Make no mistake, this work does not model the electrical behaviour of the components of the CCS. In a bid to have an insight into the patho-physiology inherent in the system, the concept of efficiency (of the CCS) was discussed using the nodal and conducting structures. Reasonable clues suggest that undue resistance to flow may be culpable in cardiac events. Keywords: circuit; source and sink; matrix; efficiency; patho-physiology.

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How to Cite this Article:

Nzerem Francis Egenti, Ugorji Hycinth Chimezie, Cardiac conduction system: the graph theoretic approach, Journal of Mathematical and Computational Science, Vol 9, No 3 (2019), 303-326

Copyright © 2019 Nzerem Francis Egenti, Ugorji Hycinth Chimezie. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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