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Commun. Math. Biol. Neurosci. 2019 (2019), Article ID 30

Analysis of nonlinear radiative microwave heating of hyperthermia tumor cells therapy in a porous medium

S.I. Oke, S.O. Salawu, M.B. Matadi, I.L. Animasaun

Abstract

This work examines the theoretical analysis of the nonlinear thermal radiation therapy that involves microwave heating of the hyperthermia tumor cell. The heat transfer is carried out in a porous medium and is time dependent. Non-dimensionalized variables and quantities were used as the main modeled equations alongside the Dirichlet boundary conditions for physical interpretation. The dimensionless equation accurately predicts the blood temperature distributions within the tissues, by using stable and unconditional convergent finite difference of semi-implicit type. Tumor cells death occurred due to increased cells sensitivity to non-linear thermal radiation and blood flow emanating from the hyperthermia treatment. The results showed that applying high metabolic heat of $3.97X10^5Wm^{-3}$ on tumor cells have a therapeutic effect.

Published
26 November 2019
Volume
2019 (2019)
License
CC BY 3.0

Copyright © 2019 S.I. Oke, S.O. Salawu, M.B. Matadi, I.L. Animasaun. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Cite this article

S. I. Oke, S. O. Salawu, M. B. Matadi, I. L. Animasaun, Analysis of nonlinear radiative microwave heating of hyperthermia tumor cells therapy in a porous medium, Commun. Math. Biol. Neurosci. 2019 (2019), 30. https://doi.org/10.28919/cmbn/4254

BibTeX
@article{Oke2019,
  author  = {Oke, S.I. and Salawu, S.O. and Matadi, M.B. and Animasaun, I.L.},
  title   = {Analysis of nonlinear radiative microwave heating of hyperthermia tumor cells therapy in a porous medium},
  journal = {Commun. Math. Biol. Neurosci.},
  volume  = {2019},
  year    = {2019},
  pages   = {30},
  doi     = {10.28919/cmbn/4254}
}