Mathematical model analysis of hepatitis C with cardiac side effects before, during, and after receiving direct acting antivirals treatment
Abstract
Hepatitis C virus (HCV) is a blood-borne infection that can lead to liver failure, cirrhosis, hepatocellular carcinoma, and death. Direct-acting antivirals (DAAs) are a relatively new therapeutic approach, the most efficient and safest hepatitis C treatment. However, DAAs can have divergent effects on heart health. The side effects of DAAs on the heart are called cardiotoxicity. Therefore, we built a mathematical model based on hepatitis C patients, showed the positivity and boundedness of the system solution, and determined the equilibrium point and its stability by exploiting the Routh Hurwitz criteria, which established an asymptotically stable equilibrium point. Finally, we performed numerical simulations to evaluate these results.
- Published
- 17 June 2024
- Volume
- 2024 (2024)
- License
- CC BY 3.0
Copyright © 2024 Chaimae El Mourabit, Nadia Idrissi Fatmi. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Cite this article
C. El Mourabit, N. Idrissi Fatmi, Mathematical model analysis of hepatitis C with cardiac side effects before, during, and after receiving direct acting antivirals treatment, Commun. Math. Biol. Neurosci. 2024 (2024), 65. https://doi.org/10.28919/cmbn/8576
BibTeX
@article{Mourabit2024,
author = {El Mourabit, Chaimae and Idrissi Fatmi, Nadia},
title = {Mathematical model analysis of hepatitis C with cardiac side effects before, during, and after receiving direct acting antivirals treatment},
journal = {Commun. Math. Biol. Neurosci.},
volume = {2024},
year = {2024},
pages = {65},
doi = {10.28919/cmbn/8576}
}