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Communications in Mathematical Biology and Neuroscience ISSN 2052-2541

Archives › Volume 2026 (2026)

Commun. Math. Biol. Neurosci. 2026 (2026), Article ID 84

Global stability analysis of a new multiscale HBV model with therapy

Ismail Aamoum, Adil Meskaf

PDF (261.7 KB) https://doi.org/10.28919/cmbn/10072

Abstract

This paper discusses the viral dynamics of hepatitis B virus with a new multi-scale model. The model studies the interaction between hepatitis B virus (HBV) and liver cells (hepatocytes) with the presence of two types of therapy. The first represents the efficacy of the treatment drug in preventing new infections, while the second represents the efficacy of the drug treatment in inhibiting viral production. The equilibrium points of the model are well defined, their global stability has been studied and the basic reproduction rate has been calculated. Finally, numerical simulations are established to confirm our theoretical results.

Published
10 September 2026
Volume
2026 (2026)
License
CC BY 3.0

Copyright © 2026 Ismail Aamoum, Adil Meskaf. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Cite this article

I. Aamoum, A. Meskaf, Global stability analysis of a new multiscale HBV model with therapy, Commun. Math. Biol. Neurosci. 2026 (2026), 84. https://doi.org/10.28919/cmbn/10072

BibTeX
@article{Aamoum2026,
  author  = {Aamoum, Ismail and Meskaf, Adil},
  title   = {Global stability analysis of a new multiscale HBV model with therapy},
  journal = {Commun. Math. Biol. Neurosci.},
  volume  = {2026},
  year    = {2026},
  pages   = {84},
  doi     = {10.28919/cmbn/10072}
}