A simplification and analysis of the HPA axis model

Pengcheng Xiao, Adam Lonnberg, Tuan Nguyen

Abstract


The human stress response is controlled largely by the hypothalamic pituitary adrenal (HPA) axis. Models predicting the levels of the hormones involved are very often not analytically solvable because of nonlinear complexity. A simplified HPA axis model with the minimum nonlinear terms including the glucocorticoid receptor (GR) is proposed. Quantitative analysis and numerical simulation related oscillating solutions are both investigated in this model.

Full Text: PDF

Published: 2018-09-12

How to Cite this Article:

Pengcheng Xiao, Adam Lonnberg, Tuan Nguyen, A simplification and analysis of the HPA axis model, Communications in Mathematical Biology and Neuroscience, Vol 2018 (2018), Article ID 18

Copyright © 2018 Pengcheng Xiao, Adam Lonnberg, Tuan Nguyen. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Commun. Math. Biol. Neurosci.

ISSN 2052-2541

Editorial Office: office@scik.org

 

Copyright ©2018 CMBN